TBX2 Polyclonal Antibody, 20ul Vortex Mixer This protein also interacts with

This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins

acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs

These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins

is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988)

Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites

TBX2 Polyclonal Antibody, 20ul Vortex Mixer This protein also interacts withTBX2 is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent.