BIG2 Polyclonal Antibody, 100ul Purification ABC genes are divided into

ABC genes are divided into seven distinct subfamilies (ABC1| MDR/TAP| MRP| ALD| OABP| GCN20| and White)

The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix

The predicted 727-amino acid human protein contains a 29-amino acid presequence

The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup

Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene

BIG2 Polyclonal Antibody, 100ul Purification ABC genes are divided intoADP ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein (ADP ribosylation factor guanine nucleotide exchange factor 2) encoded by ARFGEF2 is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine nucleotide exchange activity and also brefeldin A inhibition.