Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies TJs form an apical junctional

TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity

Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease| and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease

Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4

Bim functions in regulating apoptosis associated with thymocyte negative selection and following growth factor withdrawal

SH3 domains

Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies TJs form an apical junctionalThe protein encoded by this gene is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple