Parkin Polyclonal Antibody, 100ul Cell Culture Flasks Regulates myosin phosphatase activity

Regulates myosin phosphatase activity

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Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1)

while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes

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Parkin Polyclonal Antibody, 100ul Cell Culture Flasks Regulates myosin phosphatase activityThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have