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Rb(Phospho Ser811) Polyclonal Antibody, 100ul Cell Separation and Collection Are you ready to push

SKU: 45914361292

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PLN141.00 PLN188.00

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Rb(Phospho Ser811) Polyclonal Antibody, 100ul Cell Separation and Collection Are you ready to pushThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

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It contains a TFIID-31 domain

This protein shares strong similarity with DNA replication factor C (RFC)| and can form a complex with RFCs

Transiently dissociates following mitogenic stimulation

These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures

Rb(Phospho Ser811) Polyclonal Antibody, 100ul Cell Separation and Collection Are you ready to pushThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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