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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis while defects in this gene

SKU: 45561258617

4.6
SEK162.00 SEK206.00

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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis while defects in this geneThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

Store: gaabil.dk · Domain: gaabil.dk

Description

while defects in this gene are associated with multiple types of cancer

Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency)

EF-hand calcium binding domain 5) is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes

a region which confers cyclic nucleotide regulation of message decay

A chromosomal translocation that includes this gene is associated with Peters' anomaly

PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis while defects in this geneThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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