DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy Two pseudogenes of this gene

Two pseudogenes of this gene have been identified within this cluster on chromosome 7

It is required for pilus biogenesis

KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1

Expression of this gene is induced by estrogen and altered in some breast cancers

CCT8 encodes the theta subunit of the CCT chaperonin

DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy Two pseudogenes of this geneThe protein encoded by this gene belongs to the DMRT gene family sharing a DM DNA binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 genes involved in sex determination in these organisms. Also this gene is located in a region of the human genome (chromosome 9p24. 3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex determining gene(s) on chr 9.