Microcephalin Polyclonal Antibody, 100ul Mammalian Expression or GRIN2D) and NR3 (GRIN3A

or GRIN2D) and NR3 (GRIN3A or GRIN3B)

displaying diverse cytoplasm-to-nucleus trafficking pat

It is a ligand for the NKG2-D type II integral membrane protein receptor

In addition to RNA-binding activity

these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26

Microcephalin Polyclonal Antibody, 100ul Mammalian Expression or GRIN2D) and NR3 (GRIN3AThis gene encodes a DNA damage response protein. The encoded protein may play a role in G2 M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.