CABP2 Rabbit Polyclonal Antibody, 20ul Palm Micro Centrifuges Mutations in CBX2 are also

Mutations in CBX2 are also associated with gonadal dysgenesis in humans

Has DNA-dependent ATPase activity and binds to A/T-rich DNA

Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA)

a calcium-dependent

Expressed at lower level in neural tissues and at the highest level in the adrenal gland

CABP2 Rabbit Polyclonal Antibody, 20ul Palm Micro Centrifuges Mutations in CBX2 are alsoThis gene belongs to a subfamily of calcium binding proteins that share similarity to calmodulin. Like calmodulin these family members can likely stimulate calmodulin dependent kinase II and the protein phosphatase calcineurin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Two transcript variants encoding different isoforms have been found for this gene.