CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis The product of this gene

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins

liver and brain but not in other tissues

It forms weaker tetramer interactions than non-erythrocytic alpha spectrin| which may increase the plasma membrane elasticity and deformability of red blood cells

The chimeric transcript is an in-frame fusion of NUP98 exon 8 to PSIP1/LEDGF exon 4

Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets

CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis The product of this geneThis gene is a member of Ser Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X linked infantile spasm syndrome (ISSX), also known as X linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.