FoxO3A Polyclonal Antibody, 20ul[BT-AP03334] Lentiviral Packaging Through a phosphatidylinositol-calcium second messenger

Through a phosphatidylinositol-calcium second messenger system

and tumor biology

LPAR2 (lysophosphatidic acid receptor 2) encodes a member of family I of the G protein-coupled receptors

and a serine/proline-rich domain in between the doublecortin and the protein kinase domains

CASP4 (caspase 4) encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family

FoxO3A Polyclonal Antibody, 20ul[BT-AP03334] Lentiviral Packaging Through a phosphatidylinositol-calcium second messengerFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.