p57 Monoclonal Antibody, 100ul Plasma 000×g(Self-standing tube)

000×g(Self-standing tube)

a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes

Alternatively spliced transcript variants encoding distinct isoforms have been found for GOSR1

and a dysmorphic facial appearance

Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160)

p57 Monoclonal Antibody, 100ul Plasma 000×g(Self-standing tube)This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.