PA21B Polyclonal Antibody, 100ul 3D Cell Culture Consumables 2006 [PubMed: 16426570])

2006 [PubMed: 16426570])

Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers

have fewer positive charged residues that in other sodium channels

and some of these variants have been shown to encode more than one isoform

but also as a potent signalling molecule

PA21B Polyclonal Antibody, 100ul 3D Cell Culture Consumables 2006 [PubMed: 16426570])This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium dependent enzyme catalyzes the hydrolysis of the sn 2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs)