Topo II alpha(Phospho Ser1106) Polyclonal Antibody, 100ul Human Genome Knockout Libraries Two transcript variants encoding different

Two transcript variants encoding different isoforms have been described for this gene

The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain

This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region

fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots

There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations

Topo II alpha(Phospho Ser1106) Polyclonal Antibody, 100ul Human Genome Knockout Libraries Two transcript variants encoding differentThis gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus