TNIK Polyclonal Antibody, 100ul Buffers & Solutions Binding of 53BP1 to the

Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation

The protein encoded by EIF3D (eukaryotic translation initiation factor 3 subunit D) is the major RNA binding subunit of the eIF3 complex

It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor

including phagocytosis and cell migration

Multiple alternatively spliced transcript variants encoding the same protein have been found

TNIK Polyclonal Antibody, 100ul Buffers & Solutions Binding of 53BP1 to theGerminal center kinases (GCKs), such as TNIK, are characterized by an N terminal kinase domain and a C terminal GCK domain that serves a regulatory function (Fu et al., 1999