TXND2 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene is a member

This gene is a member of the synapsin gene family

Mutations in this gene are associated with myeloproliferative diseases

it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain

Humanized functional design

A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene| encoding a DNA binding protein| located on chromosome 11 is associated with leukemia

TXND2 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene is a memberProbably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,Contains 1 thioredoxin domain.,subcellular location: