VPS72 Polyclonal Antibody, 50ul Cell Biology MLH3 is a member of

MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes

Alternatively spliced transcript variants encoding different isoforms have been found for CXCR3

This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11

along with TAB1 and MAP3K7

which is located in its fourth intron

VPS72 Polyclonal Antibody, 50ul Cell Biology MLH3 is a member ofThe protein encoded by VPS72 (vacuolar protein sorting 72 homolog) is a shared subunit of two multi component complexes, the histone acetyltransferase complex TRRAP TIP60 as well as the chromatin remodeling SRCAP containing complex. The TRRAP TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP containing complex catalyzes the exchange of histone H2A with the