TPH2 Polyclonal Antibody, 50ul Roller Bottles Mutations in this gene have

Mutations in this gene have been associated with neurodegenerative diseases and several cancers

Detected at very low levels in brain

that is required for anchoring microtubules to subcellular structures

An important paralog of this gene is TUBGCP2

TRAF3IP3 encodes TRAF3-interacting JNK-activating modulator that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway

TPH2 Polyclonal Antibody, 50ul Roller Bottles Mutations in this gene haveTPH2 encodes a member of the pterin dependent aromatic acid hydroxylase family. The tryptophan hydroxylase 2 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.