CCNK Polyclonal Antibody, 100ul Supplements Poly [ADP-ribose] polymerase 2 has

Poly [ADP-ribose] polymerase 2 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase

Contributes to cell motility by controlling actin dynamics

It binds to collagen

Alternate splicing results in multiple transcript variants encoding distinct isoforms

head and neck cancers

CCNK Polyclonal Antibody, 100ul Supplements Poly [ADP-ribose] polymerase 2 hasThe protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin dependent kinases (CDK) that phosphorylate the C terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.