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GLK Polyclonal Antibody, 100ul Cell Dissociation DVL1 is a candidate gene

SKU: 41537027976

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GLK Polyclonal Antibody, 100ul Cell Dissociation DVL1 is a candidate geneMAP4K3 encodes a member of the mitogen activated protein kinase kinase kinase kinase family. Mitogen activated protein kinase kinase kinase kinase 3 activates key effectors in cell signalling, among them c Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Store: gaabil.dk · Domain: gaabil.dk

Description

DVL1 is a candidate gene for neuroblastomatous transformation

The normal protein may act to suppress inappropriate recombination

Through interaction with the ERBB family of receptors

Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer

These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways

GLK Polyclonal Antibody, 100ul Cell Dissociation DVL1 is a candidate geneMAP4K3 encodes a member of the mitogen activated protein kinase kinase kinase kinase family. Mitogen activated protein kinase kinase kinase kinase 3 activates key effectors in cell signalling, among them c Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

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