OREX Polyclonal Antibody, 100ul RNA Synthesis Transcript variants encoding different isoforms

Transcript variants encoding different isoforms have been described for this gene

thus in some way contributing to the regulation of the forebrain clock

Defects in this gene are associated with isolated cleft palate and mental retardation

the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions

This gene has a partial pseudogene on chromosome 1

OREX Polyclonal Antibody, 100ul RNA Synthesis Transcript variants encoding different isoformsThis gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.