FIBP Rabbit Polyclonal Antibody, 100ul Vortex Mixer The protein localizes primarily to

The protein localizes primarily to the nucleus and its expression is developmentally regulated

This gene is one of a cluster of highly related genes located at chromosomal region 19q13

RNA-binding

Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3

The protein is phosphorylated in a cell-cycle dependent manner

FIBP Rabbit Polyclonal Antibody, 100ul Vortex Mixer The protein localizes primarily toAcidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene.