IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation The opticin gene is mapped

The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1)

A processed non-transcribed pseudogene located in an intron of a sodium transporter gene on chromosome 5 has been defined for this gene

one JmjN domain and two PHD-type zinc fingers

ZNF76 (Zinc Finger Protein 76) is a Protein Coding gene

Among its related pathways are protein ubiquitylation

IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation The opticin gene is mappedIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms