TRY6 Rabbit Polyclonal Antibody, 20ul Cell Culture Flasks Mutations in this gene are

Mutations in this gene are associated with type III Stickler syndrome

Mutations in this gene cause porencephaly

alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-

Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization

The protein encoded by CFLAR (CASP8 and FADD like apoptosis regulator) is a regulator of apoptosis and is structurally similar to caspase-8

TRY6 Rabbit Polyclonal Antibody, 20ul Cell Culture Flasks Mutations in this gene areAlthough this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen