TIG1 Polyclonal Antibody, 20ul sgRNA customized design Mutations in this gene cause

Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

osteocytes

The growth hormone 1 encoded by GH1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control

Alternatively spliced transcript variants have been found for

RCC1 (regulator of chromatin condensation 1) is the only known RanGEF

TIG1 Polyclonal Antibody, 20ul sgRNA customized design Mutations in this gene causeThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.