CXCR4 Polyclonal Antibody, 50ul Immunology suggesting that they are derived

suggesting that they are derived from recent gene duplication events

This protein is expressed in brain and pancreatic cells

Several related pseudogenes have been identified

it phosphorylates TIA1

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

CXCR4 Polyclonal Antibody, 50ul Immunology suggesting that they are derivedThis gene encodes a CXC chemokine receptor specific for stromal cell derived factor 1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding