IKappaB- Alpha Polyclonal Antibody, 100ul[BT-AP04676] In vitro Assessment subcellular location:Localized in a compartment

subcellular location:Localized in a compartment adjacent to the nucleolus

Platelet derived growth factor subunit A preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A

and these interactions affect the rate of transcription initiation

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB)

IKappaB- Alpha Polyclonal Antibody, 100ul[BT-AP04676] In vitro Assessment subcellular location:Localized in a compartmentNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell