GRK2(Phospho-Tyr86) Polyclonal Antibody, 100ul Antibody Humanization Cyclin F encoded by CCNF

Cyclin F encoded by CCNF belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified

and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis

PubMed: 18503084

Rotor capacity: Micro-plates

Members of this family contain a single transmembrane domain

GRK2(Phospho-Tyr86) Polyclonal Antibody, 100ul Antibody Humanization Cyclin F encoded by CCNFThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.