11 Beta-HSD1 Polyclonal Antibody, 100ul[BT-AP00002] Adeno-associated Virus Packaging It is included in a

It is included in a cluster of homeobox D genes located on chromosome 2

tumor necrosis factor (TNF)-alpha signaling

This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers

Nkx2-6 encodes a homeobox-containing protein that belongs to the NK-2 homeobox family

The specific functions of these proteins have not been determined| but they are thought to be involved in sperm maturation

11 Beta-HSD1 Polyclonal Antibody, 100ul[BT-AP00002] Adeno-associated Virus Packaging It is included in ahydroxysteroid 11 beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and