Stat5(Phospho Tyr694/699) Polyclonal Antibody, 100ul Custom DNA Oligos Sporadic and familial mutations in

Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma

and stable gene expression

At least one pseudogene has been identified at 17p12-p11

tissue specificity:Highly expressed in brain

The protein encoded by this gene resides in the ER| and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen

Stat5(Phospho Tyr694/699) Polyclonal Antibody, 100ul Custom DNA Oligos Sporadic and familial mutations inThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM CSF, erythropoietin,