Rb Polyclonal Antibody, 100ul[BT-AP07687] Recombinant Ab Production and mutations in the gene

and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency

which catalyze the reversible hydration of carbon dioxide in various biological processes

The protein encoded by this gene is a member of the shugoshin family of proteins

which is essential for the catalytic activity

EMR4P is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration

Rb Polyclonal Antibody, 100ul[BT-AP07687] Recombinant Ab Production and mutations in the geneThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.