GHR Polyclonal Antibody, 100ul Cell Culture Dishes It is expressed only in

It is expressed only in brain and ovary

Alternative splicing of this gene results in several transcript variants

This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12

The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation

and contributes to T cell activation

GHR Polyclonal Antibody, 100ul Cell Culture Dishes It is expressed only inGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.