NR1H2 Polyclonal Antibody, 50ul Cryopreservation Maximize your potential with 100-1000

Maximize your potential with 100-1000 µl capacity

This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins| which function in the mammalian early secretory pathway

resulting in the production of a fusion protein

Its ligand

Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome)

NR1H2 Polyclonal Antibody, 50ul Cryopreservation Maximize your potential with 100-1000The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand activated LXRs form obligate heterodimers