ER Alpha Monoclonal Antibody, 100ul[BT-MCA0515] Antibody Development Mutations in the TFR2 gene

Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3)

ORC1 encodes one of several deubiquitylating enzymes

and undergoes ubiquitination and proteasome-mediated degradation

The CD84 molecule is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells

indicating a role as a negative regulator of CDC2/cyclin A

ER Alpha Monoclonal Antibody, 100ul[BT-MCA0515] Antibody Development Mutations in the TFR2 geneThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen