Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy thymus and fetal liver

thymus and fetal liver

This gene encodes a member of the forkhead class of DNA-binding proteins

It contains extracellular kringle

The encoded protein may be involved in sensory neuron regulation and in the modulation of pain

Another member of the CHP subfamily

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy thymus and fetal liverThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.