Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos as represented in GeneID: 106780802

as represented in GeneID: 106780802

It is one of the components of a multiprotein complex required for exocytosis

Mutations in this gene contribute to mitochondrial complex 1 deficiency

probably by mediating phosphorylation of dishevelled proteins (DVL1

The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration

Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos as represented in GeneID: 106780802Apurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.