F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression 2|q22) associated with T-cell acute

2|q22) associated with T-cell acute lymphoblastic leukemia

which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A

This gene product acts as a GEF preferentially for RhoG

Both actins and ARPs have an actin fold

Dysregulation of this gene has been associated with the growth and progression of certain cancers

F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression 2|q22) associated with T-cell acuteThe protein encoded by this gene is cell cycle regulated and has nuclear localization. The C terminal half of the protein shares homology with trypsin like peptidases and it contains a PCNA interacting peptide (PIP) box that is necessary for its co localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects consistent with the demonstrated role for this gene in Simian Virus 40 (SV40)