Dvl-2 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos and activates c-Jun N-terminal kinase

and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells

well-conserved family of calcium-dependent cysteine proteases

An allele of this gene was discovered that increases susceptibility to hypercholesterolemia

The function of the ataxins is not known

There is a negative correlation between the age of onset and CAG repeat numbers

Dvl-2 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos and activates c-Jun N-terminal kinaseDVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90 kD protein that undergoes posttranslational phosphorylation to form a 95 kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved