ADAR2 Polyclonal Antibody, 50ul Serum & Sample Tubes The encoded protein is a

The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes

and induces transcription of genes in response to hormonal stimulation of the cAMP pathway

Alternatively spliced transcript variants have been found| but the full-length nature of these variants is not determined

In addition| the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides| localize to promoters and CpG islands| and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2| an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA

a class of neurological and neuromuscular disorders caused by expansion of short stretches of repetitive DNA

ADAR2 Polyclonal Antibody, 50ul Serum & Sample Tubes The encoded protein is aADARB1 encodes the enzyme (adenosine deaminase, RNA specific B1) responsible for pre mRNA editing of the glutamate receptor subunit B by site specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of ADARB1 results in several transcript variants, some of which have been characterized by