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GRK 2(Phospho Ser685) Polyclonal Antibody, 50ul Recombinant Protein reduces sensitivity and enhances wearing

SKU: 35819361533

4.2
USD185.00 USD227.00

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GRK 2(Phospho Ser685) Polyclonal Antibody, 50ul Recombinant Protein reduces sensitivity and enhances wearingThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Store: gaabil.dk · Domain: gaabil.dk

Description

reduces sensitivity and enhances wearing comfort

Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility

cell proliferation and motility/migration

The protein is a cancer-associated antigen that can stimulate autologous T-cell responses| and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies| including diffuse large B-cell lymphoma

NFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes

GRK 2(Phospho Ser685) Polyclonal Antibody, 50ul Recombinant Protein reduces sensitivity and enhances wearingThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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