RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks in isoprenoid and sterol synthesis

in isoprenoid and sterol synthesis

Over-expression of this gene has been noted in gastrointestinal tract tumors

enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

This kinase is activated by various cell stimuli

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RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks in isoprenoid and sterol synthesisRUFY1 (RUN and FYVE domain containing 1) encodes a protein that contains a RUN domain and a FYVE type zinc finger domain. The encoded protein binds to phosphatidylinositol 3 phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for RUFY1.