SPTN4 Polyclonal Antibody, 20ul Cellular Function Assays The encoded protein belongs to

The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system

Evidence suggests that mitotic phosphorylation is required for its catalytic activity

Mutations in this gene may be associated with renal adysplasia

The large| uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain

a neuromuscular disorder characterized by muscle weakness and rod-shaped

SPTN4 Polyclonal Antibody, 20ul Cellular Function Assays The encoded protein belongs toSpectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha and beta subunits. This gene is one member of a family of beta spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and