GPTC8 Polyclonal Antibody, 50ul Molecular Biology The type VII collagen fibril

The type VII collagen fibril

as a common sulfate donor for sulfation of glycoproteins

a fibrillar collagen that is found in extensible connective tissues such as skin

The product of this gene belongs to the B' family

and Brooke-Spiegler syndrome

GPTC8 Polyclonal Antibody, 50ul Molecular Biology The type VII collagen fibrilThe protein encoded by this gene contains an RNA processing domain, a zinc finger domain, a lysine rich region and a serine rich region. A mutation in the serine rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms.