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PP4R1 Polyclonal Antibody, 20ul Immunology Protein phosphatase 2 holoenzymes are

SKU: 35377570213

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PP4R1 Polyclonal Antibody, 20ul Immunology Protein phosphatase 2 holoenzymes areThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

Store: gaabil.dk · Domain: gaabil.dk

Description

Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A

RGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP

Supplied in a convenient 12-piece case

It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients

An important paralog of this gene is PAQR6

PP4R1 Polyclonal Antibody, 20ul Immunology Protein phosphatase 2 holoenzymes areThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

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