HAP1 Polyclonal Antibody, 20ul Thermo Mix Rac GTPase activating protein 1

Rac GTPase activating protein 1 plays a regulatory role in cytokinesis

resulting in increased GLUT4 at the cell surface

The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends

and presumably other genes that employ IRF1 for transcription activation

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HAP1 Polyclonal Antibody, 20ul Thermo Mix Rac GTPase activating protein 1Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase