Raf-B Polyclonal Antibody, 20ul[BT-AP07630] Sealing Film Thr274 and Ser443

Thr274 and Ser443

Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor

Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation

significant expression is found in Schwann cells

Trichodentoosseous syndrome (TDO)

Raf-B Polyclonal Antibody, 20ul[BT-AP07630] Sealing Film Thr274 and Ser443BRAF (B Raf proto oncogene, serine threonine kinase) encodes a protein belonging to the raf mil family of serine threonine protein kinases. This protein plays a role in regulating the MAP kinase ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance.