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FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody, 50ul Cell Culture Plates tissue specificity:Highly expressed in placenta

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FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody, 50ul Cell Culture Plates tissue specificity:Highly expressed in placentadisease: A chromosomal aberration involving FOXO3 is found in secondary acute leukemias. Translocation t(6; 11)(q21; q23) with MLL HRX. Transcriptional activator which triggers apoptosis in the absence of survival factors including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'

Store: gaabil.dk · Domain: gaabil.dk

Description

tissue specificity:Highly expressed in placenta

This gene encodes a member of the GXGD family of aspartic proteases| which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions| as well as a member of the signal peptide peptidase-like protease (SPPL) family

GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity

The protein encoded by this gene is an RNA cytidine acetyltransferase involved in histone acetylation| tRNA acetylation| the biosynthesis of 18S rRNA| and the enhancement of nuclear architecture and chromatin organization

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FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody, 50ul Cell Culture Plates tissue specificity:Highly expressed in placentadisease: A chromosomal aberration involving FOXO3 is found in secondary acute leukemias. Translocation t(6; 11)(q21; q23) with MLL HRX. Transcriptional activator which triggers apoptosis in the absence of survival factors including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'

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