SYNJ2 Rabbit Polyclonal Antibody, 20ul Human Genome Knockout Libraries Alternatively spliced transcript variants of

Alternatively spliced transcript variants of this gene have been reported

MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC)

In mouse| deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium

such as TCR signaling

Vimentin encoded by this gene is responsible for maintaining cell shape

SYNJ2 Rabbit Polyclonal Antibody, 20ul Human Genome Knockout Libraries Alternatively spliced transcript variants ofThe gene is a member of the inositol polyphosphate 5 phosphatase family. The encoded protein interacts with the ras related C3 botulinum toxin substrate 1 which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin mediated endocytosis. Alternative splicing results in multiple transcript variants.