MSH2 Polyclonal Antibody, 100ul Vortex Mixer Chitotriosidase is secreted by activated

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients

Zinc finger proteins

The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex

The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins

liver or placenta

MSH2 Polyclonal Antibody, 100ul Vortex Mixer Chitotriosidase is secreted by activatedMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.