Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The LRP2 protein is critical

The LRP2 protein is critical for the reuptake of numerous ligands

DUF1220 copy number variations in human chromosomal region 1q21

The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds

Belongs to the cation channel sperm-associated family

Alternatively spliced variants encoding different isoforms have been reported| but their biological validity has not been determined

Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The LRP2 protein is criticalDVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90 kD protein that undergoes posttranslational phosphorylation to form a 95 kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved